Nitroxazepine 是一种治疗抑郁症的三环抗抑郁药 (TCA)。Nitroxazepin 作为 5-羟色胺去甲肾上腺素再摄取抑制剂。<BR><a href="https://www.medchemexpress.cn/GNE-495.html">GNE-495</a>产品描述：GNE-495 is a potent and Selective MAP4K4 Inhibitor with IC50 of 3.7 nM.
target: MAP4K4
IC 50: 3.7 nM
In vivo: GNE-495 shows excellent potency and good PK and was used to demonstrate in vivo efficacy in a retinal angiogenesis model recapitulating effects that are observed in the inducible Map4k4 knockout mice. IP injection of GNE-495 into newborn mice dose-dependently delays retinal vascular outgrowth.<br><br>
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已为全球多个知名企业、院校构建各种定制型化合物库。</span><br><br>产品链接：<a href="http://www.medchemexpress.cn/GNE-495.html">www.medchemexpress.cn/GNE-495.html</a><br><br></span><img style="width: 600.0px;height: 310.0px;"
src="http://img.dxycdn.com/trademd/upload/userfiles/image/2014/08/A1408605159png_small.jpg"
alt="">Purity:98%<BR>MWt:341.3612<BR>Formula:C18H19N3O4<BR>SMILES:O=C1N(CCCN(C)C)C2=CC=CC=C2OC3=CC=C([N+]([O-])=O)C=C13<BR>Pathway:Neuronal Signaling; <BR>Mechanisms:Serotonin Transporter; <BR>Research Area:Neurological Disease<BR>电话： 021-58955995<BR>网址： www.MedChemExpress.cn <BR>地址： 上海市浦东新区蔡伦路720号2号楼3层
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