OPC-28326 是一种外周血管扩张药，同时为 <b>α2-adrenergic receptor</b> 的拮抗剂，对 α2A-，α2B- 和 α2C 肾上腺素受体的 <b>K<sub>i</sub></b> 值分别为 2040，285 和 55 nM。<BR><a href="https://www.medchemexpress.cn/Mitoquinone_mesylate.html">Mitoquinone (mesylate)</a>产品描述：Mitoquinone mesylate is a <b>mitochondria</b>-targeted antioxidant designed to accumulate within mitochondria in vivo in order to protect against oxidative damage.
<i><b>In Vitro:</b></i> Mitoquinone (MitoQ) is a mitochondria-targeted antioxidant.The optimal doses for Mitoquinone (MitoQ) and DecylTPP treatment are selected from dose-response experiments during 4-h cold storage (CS). The potential protective benefits of Mitoquinone treatment against CS injury are tested initially using MitoSOX Red, a mitochondrial-targeted fluorescent dye that measures mitochondrial superoxide generation. Normal rat kidney (NRK) cells exposed to CS result in a ~2-fold increase in fluorescence due to mitochondrial superoxide compared with untreated cells. Mitoquinone offers significant protection against CS-induced mitochondrial superoxide generation; whereas the control compound DecylTPP does not offer any protection. Mitoquinone treatment markedly decreases mitochondrial superoxide generation, wher<br><br>
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已为全球多个知名企业、院校构建各种定制型化合物库。</span><br><br>产品链接：<a href="http://www.medchemexpress.cn/Mitoquinone_mesylate.html">www.medchemexpress.cn/Mitoquinone_mesylate.html</a><br><br></span><img style="width: 600.0px;height: 310.0px;"
src="http://img.dxycdn.com/trademd/upload/userfiles/image/2014/08/A1408605159png_small.jpg"
alt="">Purity:98%<BR>MWt:421.5750<BR>Formula:C26H35N3O2<BR>SMILES:CCC(NC1=C(C)C=C(C(N2CCC(N(C)CCC3=CC=CC=C3)CC2)=O)C=C1C)=O<BR>Pathway:GPCR/G Protein; <BR>Mechanisms:Adrenergic Receptor; <BR>Research Area:Cardiovascular Disease<BR>电话： 021-58955995<BR>网址： www.MedChemExpress.cn <BR>地址： 上海市浦东新区蔡伦路720号2号楼3层
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